Oncology/Cancer Splice Variant Array

Human cancer-related genes in a splice variant microarray.

SpliceExpress™ Oncology is the world’s first catalogue array for alternative splicing of oncogenes and genes relevant to cancer. Validated by two grants from the National Cancer Institute as well as corporate research partnerships, SpliceExpress™ arrays can provide new insight into tumor-induced RNA splicing. Patents pending.

SpliceExpress™ Oncology includes verified and pending genes from the SNP500 Consortium, enabling researchers to measure changes in RNA splicing induced by single-nucleotide polymorphisms that have been shown to predict genetic predisposition to cancer.

Analyzes 2,154 human oncogenes and other genes important to cancer
Detects 61,830 alternatively spliced sites including:

25,325 for alternative exons
10,702 for retained introns
36,473 for alternative acceptor and donor sites

Identifies 33,191 splice isoforms
72,949 oligonucleotide probes for alternatively spliced sites, exon junctions and gene expression
Manufactured by your choice of NimbleGen Systems or Agilent Technologies
Probes synthesized in situ on 1” x 3” glass slide
For use with standard hybridization kits and scanners from Axon, Agilent and other vendors
Catalog number: TEONC

Full service, including hybridization and data analysis, is also available.

Questions? Contact us.