Mouse and Rat Genome-Wide Exon Junction Arrays Launched by Jivan

(Nov. 30, 2005) – The first mouse and rat genome-wide exon junction arrays were launched today by Jivan Biologics, a privately held company located in Berkeley, CA. Available from a choice of manufacturers, Jivan's mouse and rat arrays enable scientists to monitor RNA splicing across the whole genome of these important model organisms, aiding many stages of drug development and testing.

"Jivan's exon junction arrays for mouse and rat build on an industry-leading microarray product line for RNA splicing," said Subha Srinivasan, PhD, CEO of Jivan Biologics. "They will shed light on the evolutionary role of alternative splicing in speciation."

Called SpliceExpress™ Mouse Spliceome and SpliceExpress™ Rat Spliceome, Jivan's new microarrays include splice site probes for exon junctions of each mouse and rat gene from the public sequencing efforts in RIKEN and the NIH.

The arrays are available as catalog products or with full service, including RNA amplification, labeling, hybridization, scanning, feature extraction and data analysis.

To validate differentially expressed splice sites identified using the arrays, Jivan offers a corresponding PCR primer pair for each gene and probe.

To purchase TransExpress™ Mouse Spliceome or TransExpress™ Rat Spliceome, visit www.jivanbio.com.

Jivan Biologics empowers scientists with new insight by providing a full catalogue of splice variant arrays to benefit all stages of the drug development pipeline: biomarkers in blood, diagnostics, target validation, toxicology and basic research.