Oncology/Cancer Alternative Splicing Array

Human cancer-related genes in a splice variant microarray.

SpliceExpress™ Oncology was the world’s first catalogue array for alternative splicing of oncogenes and genes relevant to cancer in 2004. Validated by two grants from the National Cancer Institute as well as corporate research partnerships, SpliceExpress™ arrays can provide new insight into tumor-induced RNA splicing. Patents pending.

SpliceExpress™ Oncology includes verified and pending genes from the SNP500 Consortium, enabling researchers to measure changes in RNA splicing induced by single-nucleotide polymorphisms that have been shown to predict genetic predisposition to cancer.

Product Details

Sequences:

• Genes: 2,154
• Splice isoforms: 33,191

Alternatively spliced sites:

• Exon skips: 23,325
• Intron retentions: 10,702
• Alt donor/acceptor sites: 36,473

For use with standard amplification, labeling and hybridization kits and scanners.

Related products: Apoptosis Splice Array, Cell Surface Splice Array, Human Genome Splice Array, PCR Primers.