Transcriptome Sequencing for mRNA Expression

Jivan is adapting its industry leading software for mRNA variant expression to support the next generation of high throughput transcriptome sequencing. A prototype containing the new software features is currently being tested.

As the cost of high-throughput mRNA sequencing continues to drop, it is becoming possible to measure expression of mRNA variant levels using deep sequencing. The millions of sequenced mRNA fragments often produce structurally and functionally distinct proteins from the same gene. They can arise as a result of genetic mutations or independently of them. Recent data suggests that 94% of all human genes undergo alternative splicing.

Jivan's software for mRNA sequencing will enable sensitive detection and analysis of transcript variants from expression sequencing.