
Role of hospitalization for inflammatory bowel disease in the post-biologic era
Jivan
- 0
Therapy for inflammatory bowel illness (IBD) typically requires specialised care. Whereas a lot of IBD care has shifted to the outpatient setting, hospitalizations stay a significant website of healthcare utilization and a large proportion of sufferers with inflammatory bowel illness require hospitalization or surgical procedure throughout their lifetime.
On this assessment, we strategy IBD care from the population-level with a particular give attention to hospitalization for IBD, together with the shifts from inpatient to outpatient care, the steadiness of emergency and elective hospitalizations, regionalization of specialty IBD care, and contribution of surgical procedure and endoscopy to hospitalized care.
Efficacy and Security of Twin Biologic Remedy in Sufferers With Inflammatory Bowel Illness: A Evaluation of the Literature
Utilizing 2 or extra remedy modalities to attain a synergistic impact in sufferers with refractory inflammatory bowel illness (IBD) has been an space of focus for a few years. This technique, referred to as mixture remedy, has been proposed for numerous therapeutic brokers, mostly biologics and immunomodulators.
Though the mainstay of biologic remedy for IBD has historically targeted on brokers focusing on tumor necrosis issue, the event of newer biologics with completely different targets, similar to vedolizumab and ustekinumab, has launched the opportunity of concomitant twin biologic remedy.
Twin biologic remedy has been proposed within the remedy algorithm for two kinds of sufferers with IBD: these with well-controlled luminal IBD and uncontrolled extraintestinal signs (secondary indications similar to arthritis or psoriasis) and people with refractory, uncontrolled IBD.
Up to now, the info on the efficacy and security of twin biologic remedy as a remedy for Crohn’s illness or ulcerative colitis stay fairly restricted. In actual fact, the overwhelming majority of the literature consists of case studies and case sequence. Given this paucity of high-level knowledge, physicians have appeared to bigger research on twin biologic remedy in different fields of medication, similar to rheumatology and dermatology.
The objective of this text is to summarize the present literature on using twin biologics in IBD, deal with the potential adversarial results or dangers related to mixture remedy, and spotlight future instructions in using this therapeutic modality.
Monitoring process-related impurities in biologics-host cell protein evaluation
Throughout biologics improvement, producers should reveal clearance of host cell impurities and contaminants to make sure drug purity, manufacturing course of consistency, and affected person security. Host cell proteins (HCPs) are a significant class of process-related impurities and require monitoring and documentation of their presence by means of improvement and manufacturing.
Even in residual quantities, they’re identified to have an effect on product high quality and efficacy in addition to affected person security. HCP evaluation utilizing enzyme-linked immunosorbent assay (HCP-ELISA) is the usual method, attributable to its easy dealing with, brief evaluation time, and excessive sensitivity for protein impurities.
Liquid chromatography mass spectrometry (LC-MS) is an orthogonal methodology for HCP evaluation and is more and more included in regulatory documentation. LC-MS presents benefits the place HCP-ELISA has drawbacks, e.g., the flexibility to determine and quantify particular person HCPs.
This text summarizes the obtainable data about monitoring HCPs in biologics and presents the latest tendencies in HCP evaluation with present state-of-the-art HCP measurement instruments. By means of case research, we current examples of HCP management methods which have been utilized in regulatory license purposes, utilizing an MS-based protection evaluation and HCP-ELISA and LC-MS for HCP quantification.
This offers novel perception into the speedy evolving technique of HCP evaluation. Enhancements in applied sciences to guage HCP-ELISA suitability and the implementation of orthogonal LC-MS strategies for HCP evaluation are necessary to rationally manipulate, engineer, and choose appropriate cell traces and downstream processing steps to restrict problematic HCPs.
Residual Ache within the Context of Choosing and Switching Biologic Remedy in Inflammatory Rheumatic Ailments
For a few years, inflammatory rheumatic ailments (IRDs) represented a supply of disappointment in medical care attributable to the mediocre efficacy of the obtainable therapies. A few of these ailments, like Rheumatoid Arthritis (RA) or Ankylosing Spondylitis (AS), precipitated concern within the normal inhabitants, particularly attributable to related joint deformities and subsequent disabilities.
Nevertheless, within the final 20 years, a brand new profitable class of antirheumatic medication has change into obtainable: biologic Illness-Modifying Antirheumatic Medication (bDMARDs). As a consequence of this revolutionary remedy, the times are over when joint and backbone deformities outlined the situation of an individual with RA or AS. Nonetheless, expectations are larger in the present day, and different scientific issues, (not solely solved by bDMARDs), appear to drive the drug choice through the span of rheumatic ailments.
Most of those points are lined by the time period “unmet wants.” One of the vital intriguing of such wants is the residual ache (RP) in sufferers which are in any other case within the organic remission of the illness. Current in a big proportion of the sufferers that enter remission standing, RP is poorly understood and managed. In recent times, new knowledge has change into obtainable on this space and new conceptual clarifications have occurred.
On this assessment, we clarify the varied nature of RP and the need of remedy diversification in such conditions. All in all, we imagine this situation is way extra complicated than easy ache and consists of different scientific facets, too (like fatigue or temper modifications) so the phrases Submit-Remission Syndrome (PRS), and PRS ache may be extra acceptable.

Immune Test Level Inhibitors in Major Cutaneous T-Cell Lymphomas: Biologic Rationale, Medical Outcomes and Future Views
Major cutaneous T-cell lymphomas (PCTCL) are the most typical kinds of cutaneous lymphomas, with Mycosis fungoides as essentially the most frequent subtype. Apart from early phases which normally have a superb prognosis, superior phases stay a terrific therapeutic problem with low survival charges.
Up to now, not one of the at present obtainable therapeutic choices have considerably improved the outcomes of superior cutaneous lymphomas. Latest research have demonstrated that immune-checkpoint molecules, similar to PD-1 and CTLA-4, play half within the proliferation pathways of neoplastic T-cells, in addition to in different tumors.
Radius 24-Well Cell Migration Assay, (Laminin Coated) |
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CBA-125-LN | Cell Biolabs | 24 assays | EUR 714 |
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
Radius 24-Well Cell Migration Assay, (Fibronectin Coated) |
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CBA-125-FN | Cell Biolabs | 24 assays | EUR 714 |
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
Radius 24-Well Cell Migration Assay, (ECM Array Coated) |
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CBA-125-ECM | Cell Biolabs | 24 wells | EUR 838.8 |
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
Radius 24-Well Cell Migration Assay, (Collagen I Coated) |
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CBA-125-COL | Cell Biolabs | 24 assays | EUR 714 |
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
Human RAD5IB(RAD5IB) ELISA Kit |
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QY-E05623 | Qayee Biotechnology | 96T | EUR 433.2 |
Radixin |
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E8ET1610-41 | EnoGene | 100ul | EUR 275 |
Description: Available in various conjugation types. |
RADIL siRNA |
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20-abx930794 | Abbexa |
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RADIL siRNA |
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20-abx930795 | Abbexa |
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Radicicol |
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B1533-1 | Biovision | each | EUR 235.2 |
Radicicol |
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A4067-1 | ApexBio | 1 mg | EUR 147.6 |
Description: Radicicol is an inhibitor of the ATPase/kinase with IC50 values of ?1?M, 100?M and 400?M, respectively for Hsp90, Topo VI and PDK3 [1].Radicicol inhibits the activities of Hsp90, Topo VI and PDK3 by blocking ATP binding to them. |
Radicicol |
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A4067-5 | ApexBio | 5 mg | EUR 468 |
Description: Radicicol is an inhibitor of the ATPase/kinase with IC50 values of ?1?M, 100?M and 400?M, respectively for Hsp90, Topo VI and PDK3 [1].Radicicol inhibits the activities of Hsp90, Topo VI and PDK3 by blocking ATP binding to them. |
Radicicol |
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abx076808-1mg | Abbexa | 1 mg | EUR 427.2 |
Radicicol |
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GA5957-1MG | Glentham Life Sciences | 1 mg | EUR 206.4 |
Radicicol |
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GA5957-5MG | Glentham Life Sciences | 5 mg | EUR 578.4 |
Radicinol |
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R047-1MG | TOKU-E | 1 mg | EUR 166.9 |
Description: C12H14O5 |
Radicinol |
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R047-5MG | TOKU-E | 5 mg | EUR 583.94 |
Description: C12H14O5 |
Radicicol |
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R020-1MG | TOKU-E | 1 mg | EUR 192 |
Radicicol |
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R020-5MG | TOKU-E | 5 mg | EUR 582 |
Radicicol |
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GA5957-1 | Glentham Life Sciences | 1 | EUR 92.4 |
Radicicol |
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GA5957-5 | Glentham Life Sciences | 5 | EUR 251.7 |
RADIL Rabbit pAb |
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A3455-100ul | Abclonal | 100 ul | EUR 369.6 |
RADIL Rabbit pAb |
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A3455-200ul | Abclonal | 200 ul | EUR 550.8 |
RADIL Rabbit pAb |
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A3455-20ul | Abclonal | 20 ul | Ask for price |
RADIL Rabbit pAb |
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A3455-50ul | Abclonal | 50 ul | Ask for price |
Radiprodil |
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HY-14777 | MedChemExpress | 10mg | EUR 321.6 |
RADIL antibody |
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70R-19751 | Fitzgerald | 50 ul | EUR 522 |
Description: Rabbit polyclonal RADIL antibody |
RADIL Antibody |
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47185-100ul | SAB | 100ul | EUR 302.4 |
RADIL Antibody |
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1-CSB-PA019275GA01HU | Cusabio |
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Description: A polyclonal antibody against RADIL. Recognizes RADIL from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF |
RADIL Antibody |
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E047185 | EnoGene | 100μg/100μl | EUR 255 |
Description: Available in various conjugation types. |
RADIL Antibody |
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E93455 | EnoGene | 100μg | EUR 255 |
Description: Available in various conjugation types. |
Radixin Peptide |
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45-137P | ProSci | 0.1 mg | EUR 405.6 |
Description: (IN) Radixin / RDX Peptide |
Radixin Rabbit mAb |
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A19751 | Abclonal | 20 μL | EUR 18 |
TEMPO, FREE RADICAL |
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320001 | Survival Technologies | each | Ask for price |
RADIL ELISA KIT|Human |
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EF002290 | Lifescience Market | 96 Tests | EUR 826.8 |
Human RADIL ELISA KIT |
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ELI-19556h | Lifescience Market | 96 Tests | EUR 988.8 |
Mouse Radil ELISA KIT |
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ELI-19557m | Lifescience Market | 96 Tests | EUR 1038 |
Radixin Rabbit pAb |
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E2381206 | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
Radixin Rabbit mAb |
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E2R25536 | EnoGene | 100ul | EUR 255 |
Description: Available in various conjugation types. |
Radixin antibody |
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10R-8619 | Fitzgerald | 100 ul | EUR 471.6 |
Description: Mouse monoclonal Radixin antibody |
Radixin antibody |
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22325-100ul | SAB | 100ul | EUR 468 |
Pig Radixin (RDX) ELISA Kit |
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abx556364-96tests | Abbexa | 96 tests | EUR 801.6 |
Radixin antibody |
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70R-12897 | Fitzgerald | 100 ul | EUR 548.4 |
Description: Affinity purified Rabbit polyclonal Radixin antibody |
Radixin antibody |
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70R-50313 | Fitzgerald | 100 ul | EUR 292.8 |
Description: Purified Polyclonal Radixin antibody |
Radixin Antibody |
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48955-100ul | SAB | 100ul | EUR 399.6 |
Radixin Antibody |
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48955-50ul | SAB | 50ul | EUR 286.8 |
Dog Radixin(RDX) ELISA kit |
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E08R0401-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Canine Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Radixin(RDX) ELISA kit |
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E08R0401-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Canine Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Radixin(RDX) ELISA kit |
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E08R0401-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Canine Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
anti- RADIL antibody |
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FNab07084 | FN Test | 100µg | EUR 702 |
Description: Antibody raised against RADIL |
Rat Radixin(RDX) ELISA kit |
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E02R0401-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Rat Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Radixin(RDX) ELISA kit |
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E02R0401-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Rat Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Radixin(RDX) ELISA kit |
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E02R0401-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Rat Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Radil ORF Vector (Rat) (pORF) |
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ORF074502 | ABM | 1.0 ug DNA | EUR 607.2 |
Pig Radixin(RDX) ELISA kit |
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E07R0401-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Porcine Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Radixin(RDX) ELISA kit |
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E07R0401-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Porcine Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Radixin(RDX) ELISA kit |
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E07R0401-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Porcine Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Radixin Antibody |
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R35200-100UG | NSJ Bioreagents | 100 ug | EUR 339.15 |
Description: Additional name(s) for this target protein: RDX |
RADIL (C-term) Rabbit pAb |
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E2611181 | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
Radixin Antibody |
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E38PA1994 | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
Radixin Antibody |
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E90907 | EnoGene | 100ul | EUR 255 |
Description: Available in various conjugation types. |
Radixin (RDX) Antibody |
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abx237085-100ug | Abbexa | 100 ug | EUR 577.2 |
Radixin (RDX) Antibody |
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abx237222-100ug | Abbexa | 100 ug | EUR 610.8 |
Radixin (RDX) Antibody |
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20-abx213128 | Abbexa |
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Radixin (RDX) Antibody |
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20-abx213357 | Abbexa |
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Radixin (RDX) Antibody |
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abx331845-100ul | Abbexa | 100 ul | EUR 510 |
Radixin (RDX) Antibody |
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20-abx327276 | Abbexa |
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Radixin (RDX) Antibody |
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abx027746-400ul | Abbexa | 400 ul | EUR 627.6 |
Radixin (RDX) Antibody |
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abx027746-80l | Abbexa | 80 µl | EUR 343.2 |
Radixin (RDX) Antibody |
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20-abx130947 | Abbexa |
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Radixin (RDX) Antibody |
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abx431560-200ul | Abbexa | 200 ul | EUR 460.8 |
Radixin (RDX) Antibody |
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20-abx008781 | Abbexa |
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Radixin (RDX) Antibody |
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20-abx014777 | Abbexa |
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Radixin (RDX) Antibody |
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abx145069-100ug | Abbexa | 100 ug | EUR 469.2 |
Goat Radixin(RDX) ELISA kit |
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E06R0401-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Goat Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Radixin(RDX) ELISA kit |
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E06R0401-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Goat Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Radixin(RDX) ELISA kit |
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E06R0401-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Goat Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Radixin ELISA KIT|Human |
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EF002292 | Lifescience Market | 96 Tests | EUR 826.8 |
Radixin Antibody / RDX |
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RQ5597 | NSJ Bioreagents | 100 ug | EUR 356.15 |
Description: Radixin is a protein that in humans is encoded by the RDX gene. Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Mouse Radixin (RDX) ELISA Kit |
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abx390396-96tests | Abbexa | 96 tests | EUR 1093.2 |
Human Radixin (RDX) ELISA Kit |
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abx382665-96tests | Abbexa | 96 tests | EUR 1093.2 |
RADIL cloning plasmid |
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CSB-CL853440HU1-10ug | Cusabio | 10ug | EUR 279.6 |
Description: A cloning plasmid for the RADIL gene. |
RADIL cloning plasmid |
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CSB-CL853440HU2-10ug | Cusabio | 10ug | EUR 1383.6 |
Description: A cloning plasmid for the RADIL gene. |
Human Radixin, RDX ELISA KIT |
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ELI-52297h | Lifescience Market | 96 Tests | EUR 988.8 |
anti- Radixin antibody |
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FNab07085 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against Radixin |
RADIL ORF Vector (Human) (pORF) |
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ORF008558 | ABM | 1.0 ug DNA | EUR 114 |
RADIL ORF Vector (Human) (pORF) |
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ORF014236 | ABM | 1.0 ug DNA | EUR 424.8 |
Mouse Radixin(RDX) ELISA kit |
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E03R0401-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Mouse Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Radixin(RDX) ELISA kit |
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E03R0401-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Mouse Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Radixin(RDX) ELISA kit |
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E03R0401-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Mouse Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Radixin(RDX) ELISA kit |
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E01R0401-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Human Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Radixin(RDX) ELISA kit |
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E01R0401-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Human Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Radixin(RDX) ELISA kit |
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E01R0401-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Human Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Radil ORF Vector (Mouse) (pORF) |
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ORF055517 | ABM | 1.0 ug DNA | EUR 607.2 |
Mouse Rdx/ Radixin ELISA Kit |
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E1693Mo | Sunlong | 1 Kit | EUR 758.4 |
Human RDX/ Radixin ELISA Kit |
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E2948Hu | Sunlong | 1 Kit | EUR 726 |
Mouse Radixin, Rdx ELISA KIT |
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ELI-18280m | Lifescience Market | 96 Tests | EUR 1038 |
Radioprotectin-1 |
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HY-114380 | MedChemExpress | 100mg | EUR 4605.6 |
Human Radixin(RDX)ELISA Kit |
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QY-E03349 | Qayee Biotechnology | 96T | EUR 433.2 |
Radil 3'UTR GFP Stable Cell Line |
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TU267261 | ABM | 1.0 ml | Ask for price |
Radil 3'UTR GFP Stable Cell Line |
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TU167484 | ABM | 1.0 ml | Ask for price |
RADIL 3'UTR GFP Stable Cell Line |
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TU069452 | ABM | 1.0 ml | EUR 2799.6 |
Mouse RADIL shRNA Plasmid |
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20-abx981920 | Abbexa |
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Human RADIL shRNA Plasmid |
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20-abx960841 | Abbexa |
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Human Radixin (RDX) Protein |
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20-abx650171 | Abbexa |
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Bovine Radixin, RDX ELISA KIT |
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ELI-52296b | Lifescience Market | 96 Tests | EUR 1113.6 |
Rabbit Radixin(RDX) ELISA kit |
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E04R0401-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Rabbit Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Radixin(RDX) ELISA kit |
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E04R0401-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Rabbit Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Radixin(RDX) ELISA kit |
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E04R0401-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Rabbit Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Radixin(RDX) ELISA kit |
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E09R0401-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Monkey Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Radixin(RDX) ELISA kit |
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E09R0401-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Monkey Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Radixin(RDX) ELISA kit |
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E09R0401-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Monkey Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Vigna radiata Lectin (VRA) - Cy3 |
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21761181-1 | Bio-WORLD | - | EUR 143.12 |
Vigna radiata Lectin (VRA) - Cy5 |
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21761182-1 | Bio-WORLD | - | EUR 143.12 |
Radixin antibody (Thr558) |
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70R-35915 | Fitzgerald | 100 ug | EUR 392.4 |
Description: Rabbit polyclonal Radixin antibody (Thr558) |
Porcine Radixin, RDX ELISA KIT |
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ELI-52490p | Lifescience Market | 96 Tests | EUR 1113.6 |
Guinea pig Radixin(RDX) ELISA kit |
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E05R0401-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Guinea pig Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig Radixin(RDX) ELISA kit |
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E05R0401-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Guinea pig Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig Radixin(RDX) ELISA kit |
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E05R0401-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Guinea pig Radixin(RDX) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Chicken Radixin, RDX ELISA KIT |
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ELI-43072c | Lifescience Market | 96 Tests | EUR 1113.6 |
Recombinant Radixin (RDX) |
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4-RPC774Hu01 | Cloud-Clone |
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Description: Recombinant Human Radixin expressed in: E.coli |
Lab Tape Radioactive 25mm x 66m |
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SAF9016 | Scientific Laboratory Supplies | 1ROLL | EUR 55.36 |
Vigna radiata Lectin (VRA) - Pure |
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21510940-1 | Bio-WORLD | - | EUR 120.4 |
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Therefore, the potential function of immune-checkpoint-inhibitors in treating cutaneous lymphomas has been investigated within the final years. Herein, we define the present data concerning the function of immune-checkpoint molecules in PCTCL, their signaling pathways, microenvironment and therapeutic inhibition rationale. Furthermore, we assessment the printed knowledge on immunotherapies in PCTCL and summarize the at present ongoing scientific trials on this subject.
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