Impact of switching on pharmacokinetics of therapeutic biologics and interchangeability assessment- a simulation study
The danger by way of security or diminished efficacy of switching between an originator organic product and a proposed interchangeable product is a vital consideration for interchangeability analysis within the regulatory framework.
This simulation examine evaluated the impression of a number of switching examine design situations on the pharmacokinetic (PK) evaluation between a digital originator organic product and a digital proposed interchangeable product.
Our outcomes present that: 1) no less than three switches are wanted to optimize the detection of potential PK variations, 2) the preliminary incidence of anti-drug antibodies (ADA) after therapy with the reference product within the lead-in interval is a big covariate affecting the PK outcomes, and three) the world underneath the concentration-time curve is extra delicate than peak focus in assessing the impression of switching on PK similarity.
Our simulation work illustrates {that a} vary of things ought to be fastidiously thought-about when designing a switching examine for the evaluation of interchangeability between two organic merchandise. This text is protected by copyright. All rights reserved.
Biologic therapy for psoriasis in most cancers sufferers: ought to they nonetheless be thought-about forbidden?
Obtainable proof to information clinicians within the administration of psoriasis sufferers with a historical past of malgnancies is scarce. The newest technology of organic medication is historically thought-about to be secure in sufferers with earlier malignancy, though solely case reviews and brief case sequence on using organic medication on this inhabitants can be found within the literature.
On this paper, we current the expertise of our clinic on 37 psoriatic sufferers with a earlier analysis of neoplasia handled subsequently with organic medication. Subsequently, a scientific evaluation of the literature was carried out and 38 instances had been discovered. The primary biologic utilized in our sufferers and the sufferers described within the literature was secukinumab.
In each populations therapy with biologics was secure, illness progressions reported weren’t associated to therapy.Based mostly on our expertise, which is the most important at the moment accessible, and the instances reported within the literature the therapy of psoriasis in sufferers with beforehand recognized most cancers with biologics towards TNFalpha, IL17, IL23 and IL12 would seem like secure. The primary expertise on using Risankizumab and brodalumab on this particular inhabitants can be reported in our sequence.
A Complete Literature Evaluate and Professional Consensus Assertion on Therapeutic Drug Monitoring of Biologics in Inflammatory Bowel Illness
Therapeutic drug monitoring (TDM) of biologics is a quickly evolving subject. We aimed to offer a consensus assertion relating to the scientific utility of TDM for biologics in inflammatory bowel illness (IBD). A modified Delphi technique was utilized to develop consensus statements.
A complete literature evaluation was carried out relating to TDM of biologic therapies in IBD, and 45 statements had been subsequently formulated on the potential software of TDM in IBD. The statements, together with literature, had been then offered to a panel of 10 gastroenterologists with experience in IBD and TDM who anonymously rated them on a scale of 1-10 (1 = strongly disagree and 10 = strongly agree).
An skilled consensus growth assembly was held just about to evaluation, focus on, refine, and reformulate statements that didn’t meet standards for settlement or that had been ambiguous. Throughout the assembly, further statements had been proposed.
Panelists then confidentially revoted, and statements rated ≥7 by 80% or extra of the members had been accepted. Throughout the digital assembly, eight statements had been reworded, 7 new statements had been proposed, and 19 statements had been rerated.
Consensus was lastly reached in 48/49 statements. The panel agreed that reactive TDM ought to be used for all biologics for each major nonresponse and secondary lack of response. It was really helpful that therapy discontinuation shouldn’t be thought-about for infliximab or adalimumab till a drug focus of no less than 10-15 μg/mL was achieved.
Consensus was additionally achieved relating to the utility of proactive TDM for anti-tumor necrosis issue remedy. It was really helpful to carry out proactive TDM after induction and no less than as soon as throughout upkeep. Consensus was achieved normally relating to the utility of TDM of biologics in IBD, particularly for reactive and proactive TDM of anti-tumor necrosis components.
ImmTORTM to amplify the efficacy and cut back immunogenicity of biologics
In latest months as vaccines towards the SARS-CoV-2 virus proceed to rollout throughout the globe, there was a renewed curiosity in methods to activate or ignite the immune system. For a vaccine to be efficient, it should be immunogenic and particular to impress the physique’s defenses to mount an efficient response that protects the host from illness.
Nonetheless, there are different conditions whereby the immune system mounts an undesirable immune response that may be detrimental to well being, both immediately, by inflicting an autoimmune illness, or not directly, by compromising the security and/or efficacy of biologic medication.
In these situations, it might be fascinating to have a ‘tolerogenic vaccine’ that might selectively and successfully mitigate these undesirable immune responses. ImmTORTM, a nanoparticle know-how, is being developed to handle the difficulty of immunogenicity for gene remedy vectors and different biologic medication.
By focusing on antigen-presenting cells, ImmTORTM has the potential to amplify the efficacy of biologic therapies and unlock the total potential of such therapies to enhance the lives of those that endure from critical and debilitating ailments.
Biologic and Esthetic Final result of CAD/CAM Customized Ceramic Implant Abutment: A Scientific Report
A prerequisite of a useful and esthetical implant-supported crown is a correct surgical planning and an abutment with a design and coloration that keep the preliminary soft-tissue contour.
This scientific report describes using a customized ceramic implant abutment designed with computer-aided design and computer-aided manufacturing (CAD/CAM) know-how.
A zirconia framework was milled and cemented further orally to a prefabricated titanium base, the brand new customized abutment being each exact and esthetic.
New insights into the microscopic interactions related to the bodily mechanism of motion of extremely diluted biologics
On this investigation, we report the impact on the microscopic dynamics and interactions of the cytokine interferon gamma (IFN-γ) and antibodies to IFN-γ (anti-IFN-γ) and to the interferon gamma receptor 1 (anti-IFNGR1) ready in exceptionally dilute options of preliminary proteins.
Utilizing each THz spectroscopy and molecular dynamics simulations now we have uncovered that the excessive dilution technique of pattern preparation leads to the reorganization of the pattern floor residue dynamics on the solvent-protein interface that results in each structural and kinetic heterogeneous dynamics that in the end create interactions that improve the binding chance of the antigen binding website.
BCIP (Molecular Biology Grade) |
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| CE109 | GeneOn | 1 g | EUR 108 |
CHAPS (Molecular Biology Grade) |
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| CE114 | GeneOn | 1 g | EUR 66 |
CHAPS (Molecular Biology Grade) |
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| CE115 | GeneOn | 5 g | EUR 157.2 |
CHAPS (Molecular Biology Grade) |
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| CE116 | GeneOn | 25 g | EUR 492 |
DAPI (Molecular Biology Grade) |
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| CE117 | GeneOn | 5 mg | EUR 72 |
DAPI (Molecular Biology Grade) |
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| CE118 | GeneOn | 25 mg | EUR 159.6 |
DAPI (Molecular Biology Grade) |
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| CE119 | GeneOn | 100 mg | EUR 382.8 |
Dimethylsulfoxide (Molecular Biology Grade) |
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| CE120 | GeneOn | 100 ml | EUR 66 |
Dimethylsulfoxide (Molecular Biology Grade) |
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| CE121 | GeneOn | 500 ml | EUR 110.4 |
DTT (Molecular Biology Grade) |
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| CE131 | GeneOn | 5 g | EUR 93.6 |
DTT (Molecular Biology Grade) |
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| CE132 | GeneOn | 10 g | EUR 133.2 |
DTT (Molecular Biology Grade) |
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| CE133 | GeneOn | 25 g | EUR 243.6 |
Glycine (Molecular Biology Grade) |
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| CE158 | GeneOn | 1 kg | EUR 84 |
Glycine (Molecular Biology Grade) |
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| CE159 | GeneOn | 5 kg | EUR 228 |
HEPES (Molecular Biology Grade) |
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| CE171 | GeneOn | 100 g | EUR 98.4 |
HEPES (Molecular Biology Grade) |
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| CE172 | GeneOn | 500 g | EUR 268.8 |
HEPES (Molecular Biology Grade) |
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| CE173 | GeneOn | 1 kg | EUR 424.8 |
Lysozyme (Molecular Biology Grade) |
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| CE188 | GeneOn | 1 g | EUR 70.8 |
Lysozyme (Molecular Biology Grade) |
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| CE189 | GeneOn | 10 g | EUR 247.2 |
NAD (Molecular Biology Grade) |
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| CE196 | GeneOn | 1 g | EUR 72 |
NAD (Molecular Biology Grade) |
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| CE197 | GeneOn | 5 g | EUR 165.6 |
NBT (Molecular Biology Grade) |
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| CE209 | GeneOn | 1 g | EUR 123.6 |
NBT (Molecular Biology Grade) |
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| CE210 | GeneOn | 5 g | EUR 360 |
Tris (Molecular Biology Grade) |
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| CE237 | GeneOn | 500 g | EUR 106.8 |
Tris (Molecular Biology Grade) |
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| CE238 | GeneOn | 1 kg | EUR 153.6 |
Tris (Molecular Biology Grade) |
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| CE239 | GeneOn | 5 kg | EUR 535.2 |
Tween20 (Molecular Biology Grade) |
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| CE242 | GeneOn | 1 l | EUR 106.8 |
Water (Molecular Biology Grade) |
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| CE243 | GeneOn | 500 ml | EUR 62.4 |
Water (Molecular Biology Grade) |
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| CE244 | GeneOn | 1 l | EUR 67.2 |
100mL Molecular Biology Grade |
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| 46-000-CI | Scientific Laboratory Supplies | PK6 | EUR 70.68 |
500mL Molecular Biology Grade |
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| 46-000-CV | Scientific Laboratory Supplies | PK6 | EUR 124.26 |
Ammonium sulfate (Molecular Biology Grade) |
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| CE105 | GeneOn | 250 g | EUR 55.2 |
Ammonium sulfate (Molecular Biology Grade) |
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| CE106 | GeneOn | 1 kg | EUR 72 |
Ammonium sulfate (Molecular Biology Grade) |
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| CE107 | GeneOn | 5 kg | EUR 153.6 |
Bis-Acrylamid (Molecular Biology Grade) |
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| CE110 | GeneOn | 50 g | EUR 94.8 |
Bis-Acrylamid (Molecular Biology Grade) |
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| CE111 | GeneOn | 250 g | EUR 259.2 |
Formamide deionized (Molecular Biology Grade) |
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| CE145 | GeneOn | 500 ml | EUR 87.6 |
Formamide deionized (Molecular Biology Grade) |
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| CE146 | GeneOn | 1 l | EUR 120 |
Glycerol 87 % (Molecular Biology Grade) |
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| CE154 | GeneOn | 1 l | EUR 93.6 |
Glycerol waterfree (Molecular Biology Grade) |
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| CE155 | GeneOn | 500 ml | EUR 78 |
Glycerol waterfree (Molecular Biology Grade) |
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| CE156 | GeneOn | 1 l | EUR 102 |
Glycerol waterfree (Molecular Biology Grade) |
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| CE157 | GeneOn | 2.5 l | EUR 170.4 |
Guanidine - Hydrochloride (Molecular Biology Grade) |
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| CE160 | GeneOn | 100 g | EUR 93.6 |
Guanidine - Hydrochloride (Molecular Biology Grade) |
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| CE161 | GeneOn | 250 g | EUR 153.6 |
Guanidine - Hydrochloride (Molecular Biology Grade) |
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| CE162 | GeneOn | 500 g | EUR 232.8 |
Guanidine - Hydrochloride (Molecular Biology Grade) |
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| CE163 | GeneOn | 1 kg | EUR 352.8 |
Guanidine Thiocyanate (Molecular Biology Grade) |
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| CE164 | GeneOn | 100 g | EUR 86.4 |
Guanidine Thiocyanate (Molecular Biology Grade) |
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| CE165 | GeneOn | 500 g | EUR 192 |
Guanidine Thiocyanate (Molecular Biology Grade) |
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| CE166 | GeneOn | 1 kg | EUR 307.2 |
MOPS buffer (Molecular Biology Grade) |
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| CE194 | GeneOn | 100 g | EUR 102 |
MOPS buffer (Molecular Biology Grade) |
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| CE195 | GeneOn | 250 g | EUR 169.2 |
Sodium chloride (Molecular Biology Grade) |
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| CE205 | GeneOn | 500 g | EUR 62.4 |
Sodium chloride (Molecular Biology Grade) |
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| CE206 | GeneOn | 1 kg | EUR 70.8 |
Sodium chloride (Molecular Biology Grade) |
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| CE207 | GeneOn | 5 kg | EUR 123.6 |
D(+)-Sucrose (Molecular Biology Grade) |
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| CE224 | GeneOn | 500 g | EUR 67.2 |
D(+)-Sucrose (Molecular Biology Grade) |
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| CE225 | GeneOn | 1 kg | EUR 84 |
D(+)-Sucrose (Molecular Biology Grade) |
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| CE226 | GeneOn | 5 kg | EUR 207.6 |
Tris - Hydrochloride (Molecular Biology Grade) |
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| CE234 | GeneOn | 250 g | EUR 99.6 |
Tris - Hydrochloride (Molecular Biology Grade) |
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| CE235 | GeneOn | 500 g | EUR 144 |
Tris - Hydrochloride (Molecular Biology Grade) |
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| CE236 | GeneOn | 1 kg | EUR 223.2 |
TritonX-100 (Molecular Biology Grade) |
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| CE240 | GeneOn | 500 ml | EUR 67.2 |
TritonX-100 (Molecular Biology Grade) |
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| CE241 | GeneOn | 1 l | EUR 79.2 |
Water, Ultrapure Molecular Biology Grade |
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| 41024-4L | Biotium | 4L | EUR 145.2 |
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Description: Minimum order quantity: 1 unit of 4L |
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Tween 20, Molecular Biology Grade |
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| T9100-010 | GenDepot | 100ml | EUR 86.4 |
Tween 20, Molecular Biology Grade |
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| T9100-050 | GenDepot | 500ml | EUR 133.2 |
Tween 20, Molecular Biology Grade |
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| T9100-100 | GenDepot | 1L | EUR 160.8 |
1L Molecular Biology Grade Water |
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| 46-000-CM | Scientific Laboratory Supplies | PK6 | EUR 177.84 |
Water, distilled, GlenBiol™, suitable for molecular biology |
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| GK8512-1L | Glentham Life Sciences | 1 l | EUR 92.4 |
Agarose, low EEO, GlenBiol, suitable for molecular biology |
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| GE6258-100G | Glentham Life Sciences | 100 g | EUR 217.2 |
Crystalline |
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| 5-01010 | CHI Scientific | 10mg | Ask for price |
EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade) |
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| CE135 | GeneOn | 250 g | EUR 72 |
EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade) |
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| CE136 | GeneOn | 500 g | EUR 86.4 |
EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade) |
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| CE137 | GeneOn | 1 kg | EUR 124.8 |
EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade) |
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| CE138 | GeneOn | 5 kg | EUR 418.8 |
D(+)-Glucose waterfree (Molecular Biology Grade) |
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| CE148 | GeneOn | 500 g | EUR 67.2 |
D(+)-Glucose waterfree (Molecular Biology Grade) |
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| CE149 | GeneOn | 1 kg | EUR 75.6 |
D(+)-Glucose waterfree (Molecular Biology Grade) |
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| CE150 | GeneOn | 5 kg | EUR 180 |
Yeast extract powder (Molecular Biology Grade) |
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| CE169 | GeneOn | 500 g | EUR 133.2 |
Hyaluronidase Grade I (Molecular Biology Grade) |
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| CE174 | GeneOn | 1 g | EUR 232.8 |
Hyaluronidase Grade I (Molecular Biology Grade) |
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| CE175 | GeneOn | 5 g | EUR 920.4 |
Magnesium acetate - Tetrahydrate (Molecular Biology Grade) |
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| CE190 | GeneOn | 500 g | EUR 98.4 |
NADH - Disodium salt (Molecular Biology Grade) |
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| CE198 | GeneOn | 1 g | EUR 91.2 |
NADH - Disodium salt (Molecular Biology Grade) |
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| CE199 | GeneOn | 5 g | EUR 244.8 |
NADP - sodium salt (Molecular Biology Grade) |
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| CE200 | GeneOn | 250 mg | EUR 92.4 |
NADP - sodium salt (Molecular Biology Grade) |
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| CE201 | GeneOn | 1 g | EUR 190.8 |
NADPH - Tetrasodium salt (Molecular Biology Grade) |
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| CE202 | GeneOn | 25 mg | EUR 70.8 |
NADPH - Tetrasodium salt (Molecular Biology Grade) |
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| CE203 | GeneOn | 100 mg | EUR 126 |
NADPH - Tetrasodium salt (Molecular Biology Grade) |
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| CE204 | GeneOn | 500 mg | EUR 374.4 |
SSC Buffer (20X) (Molecular Biology Grade) |
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| CE229 | GeneOn | 1 l | EUR 86.4 |
XTT sodium salt (Molecular Biology Grade) |
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| CE250 | GeneOn | 100 mg | EUR 208.8 |
XTT sodium salt (Molecular Biology Grade) |
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| CE251 | GeneOn | 500 mg | EUR 612 |
Albumin fraction V (pH7,0) (Molecular Biology Grade) |
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| CE100 | GeneOn | 50 g | EUR 128.4 |
Albumin fraction V (pH7,0) (Molecular Biology Grade) |
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| CE101 | GeneOn | 100 g | EUR 193.2 |
Albumin fraction V (pH7,0) (Molecular Biology Grade) |
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| CE102 | GeneOn | 250 g | EUR 387.6 |
Albumin fraction V (pH7,0) (Molecular Biology Grade) |
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| CE103 | GeneOn | 500 g | EUR 656.4 |
Albumin fraction V (pH7,0) (Molecular Biology Grade) |
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| CE104 | GeneOn | 1 kg | EUR 1162.8 |
Water, Ultra Pure, Sterile Molecular Biology Grade |
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| 18-193 | Genesee Scientific | 100ml/Unit | EUR 268 |
Water, Ultra Pure, Sterile Molecular Biology Grade |
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| 18-194 | Genesee Scientific | 500ml/Unit | EUR 294 |
Water, Ultra Pure, Sterile Molecular Biology Grade |
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| 18-195 | Genesee Scientific | 1000ml/Unit | EUR 308 |
Water, Ultra Pure, Sterile Molecular Biology Grade |
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| 18-196 | Genesee Scientific | 4 x 1L/Unit | EUR 471 |
EDTA solution pH 8.0 (0.5 M) (Molecular Biology Grade) |
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| CE141 | GeneOn | 500 ml | EUR 87.6 |
LB-Agar - Powder according to Lennox (Molecular Biology Grade) |
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| CE178 | GeneOn | 500 g | EUR 109.2 |
LB-Agar - Powder according to Lennox (Molecular Biology Grade) |
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| CE179 | GeneOn | 2.5 kg | EUR 301.2 |
LB-Agar - Powder according to Miller (Molecular Biology Grade) |
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| CE180 | GeneOn | 500 g | EUR 104.4 |
LB-Agar - Powder according to Miller (Molecular Biology Grade) |
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| CE181 | GeneOn | 2.5 kg | EUR 295.2 |
LB-Medium - Powder according to Lennox (Molecular Biology Grade) |
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| CE182 | GeneOn | 500 g | EUR 108 |
LB-Medium - Powder according to Lennox (Molecular Biology Grade) |
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| CE183 | GeneOn | 2.5 kg | EUR 301.2 |
LB-Medium - Powder according to Miller (Molecular Biology Grade) |
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| CE184 | GeneOn | 2.5 kg | EUR 295.2 |
Agarose LE, Ultra-Pure Molecular Biology Grade, 100 g |
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| 41028-100G | Biotium | 100G | EUR 266.4 |
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Description: Minimum order quantity: 1 unit of 100G |
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Agarose LE, Ultra-Pure Molecular Biology Grade, 25 g |
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| 41028-25G | Biotium | 25G | EUR 130.8 |
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Description: Minimum order quantity: 1 unit of 25G |
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Agarose LE, Ultra-Pure Molecular Biology Grade, 500 g |
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| 41028-500G | Biotium | 500G | EUR 862.8 |
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Description: Minimum order quantity: 1 unit of 500G |
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AGAROSE LE, LOW EEO, MOLECULAR BIOLOGY GRADE, 100G PER UNIT |
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| AGR-LE-100 | CORNING | 1/pk | EUR 201.6 |
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Description: Bioscience Mol Bio; Agarose |
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Bulk Beads Zr 0.1mm Triple-Pure Molecular Biology Grade 250g |
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| HOM3048 | Scientific Laboratory Supplies | 250G | EUR 536.94 |
Bulk Beads Zr 0.5mm Triple-Pure Molecular Biology Grade 250g |
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| HOM3050 | Scientific Laboratory Supplies | 250G | EUR 536.94 |
Bulk Beads Zr 1.0mm Triple-Pure Molecular Biology Grade 250g |
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| HOM3052 | Scientific Laboratory Supplies | 250G | EUR 536.94 |
Bulk Beads Zr 1.5mm Triple-Pure Molecular Biology Grade 250g |
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| HOM3054 | Scientific Laboratory Supplies | 250G | EUR 536.94 |
Bulk Beads Zr 3.0mm Triple-Pure Molecular Biology Grade 300g |
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| HOM3056 | Scientific Laboratory Supplies | 300G | EUR 536.94 |
Phenol |
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| 20-abx184753 | Abbexa |
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Phenol |
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| S-3030 | Scientific Laboratory Supplies | 1ML | EUR 38.76 |
AGAROSE LE, LOW EEO, MOLECULAR BIOLOGY GRADE, 500G/UNIT, 10 UNITS PER CASE |
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| AGR-LE-5001 | CORNING | 1/pk | EUR 3669.6 |
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Description: Bioscience Mol Bio; Agarose |
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AGAROSE MS, PCR SCREENING, MOLECULAR BIOLOGY GRADE, 100G/UNIT, 10 UNITS PER CASE |
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| AGR-MS-1001 | CORNING | 1/pk | EUR 2445.6 |
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Description: Bioscience Mol Bio; Agarose |
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Hettich Lid For Rotor Phenol Resistant |
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| CEN0811 | Scientific Laboratory Supplies | EACH | EUR 282.72 |
AGAROSE LE, LOW EEO, MOLECULAR BIOLOGY GRADE, 100G PER UNIT, 10 UNITS PER CASE |
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| AGR-LE-1001 | CORNING | 1/pk | EUR 926.4 |
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Description: Bioscience Mol Bio; Agarose |
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AGAROSE LM, LOW MELTING, MOLECULAR BIOLOGY GRADE, 100G/UNIT, 10 UNITS PER CASE (AL) |
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| AGR-LM-1001 | CORNING | 1/pk | EUR 4484.4 |
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Description: Bioscience Mol Bio; Agarose |
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AGAROSE LM, LOW MELTING, MOLECULAR BIOLOGY GRADE, 50G/UNIT, 10 UNITS PER CASE (AL) |
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| AGR-LM-501 | CORNING | 1/pk | EUR 2490 |
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Description: Bioscience Mol Bio; Agarose |
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Crystalline [H-Trp-Gly-OH; MW: 261.2] |
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| SP-55342-1 | Alpha Diagnostics | 1 mg | EUR 169.2 |
2 Deoxyadenosine 5Triphosphate Disodium Crystalline dATP 250mg |
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| 27185004 | Scientific Laboratory Supplies | EACH | EUR 355.68 |
Nonyl Phenol |
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| AG037 | Unibiotest | 1 mg | EUR 627.6 |
Water Phenol |
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| abx082109-250ml | Abbexa | 250 ml | EUR 226.8 |
Nonyl Phenol |
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| AT037 | Unibiotest | 1mg | EUR 1641.6 |
Phenol, 99% |
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| GK6990-100G | Glentham Life Sciences | 100 g | EUR 52.8 |
Phenol, 99% |
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| GK6990-1KG | Glentham Life Sciences | 1 kg | EUR 93.6 |
Phenol, 99% |
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| GK6990-500G | Glentham Life Sciences | 500 g | EUR 67.2 |
Phenol Red |
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| GT9844-100G | Glentham Life Sciences | 100 g | EUR 132 |
Phenol Red |
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| GT9844-250G | Glentham Life Sciences | 250 g | EUR 217.2 |
Phenol Red |
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| GT9844-25G | Glentham Life Sciences | 25 g | EUR 74.4 |
Phenol Red |
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| GT9844-5G | Glentham Life Sciences | 5 g | EUR 55.2 |
Phenol red |
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| PB0420 | Bio Basic | 25g | EUR 85.06 |
Phenol-d6 |
|||
| S-3035 | Scientific Laboratory Supplies | 1ML | EUR 38.76 |
ELISA kit for Human PST (Phenol Sulfotransferase) |
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| ELK3246 | ELK Biotech | 1 plate of 96 wells | EUR 518.4 |
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Description: A sandwich ELISA kit for detection of Phenol Sulfotransferase from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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ELISA kit for Mouse PST (Phenol Sulfotransferase) |
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| ELK3642 | ELK Biotech | 1 plate of 96 wells | EUR 518.4 |
|
Description: A sandwich ELISA kit for detection of Phenol Sulfotransferase from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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ELISA kit for Rat PST (Phenol Sulfotransferase) |
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| ELK6740 | ELK Biotech | 1 plate of 96 wells | EUR 518.4 |
|
Description: A sandwich ELISA kit for detection of Phenol Sulfotransferase from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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Phenol Std Phenol 2000ug/mL in MeOH |
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| REPHE110 | Scientific Laboratory Supplies | 1ML | EUR 88.92 |
Phenol Std Phenol 100ug/mL in DCM |
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| REPHE119 | Scientific Laboratory Supplies | 1ML | EUR 43.32 |
Phenol Red Solution |
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| CA013-010 | GenDepot | 100ml | EUR 82.8 |
Our outcomes point out that the modified interfacial dynamics of anti-IFN-γ and anti-IFGNR1 that we probe experimentally are immediately related to alterations within the complementarity areas of the distinct antibodies that designate each antigen-antibody affinity and recognition.
