Impact of switching on pharmacokinetics of therapeutic biologics and interchangeability assessment- a simulation study
The danger by way of security or diminished efficacy of switching between an originator organic product and a proposed interchangeable product is a vital consideration for interchangeability analysis within the regulatory framework.
This simulation examine evaluated the impression of a number of switching examine design situations on the pharmacokinetic (PK) evaluation between a digital originator organic product and a digital proposed interchangeable product.
Our outcomes present that: 1) no less than three switches are wanted to optimize the detection of potential PK variations, 2) the preliminary incidence of anti-drug antibodies (ADA) after therapy with the reference product within the lead-in interval is a big covariate affecting the PK outcomes, and three) the world underneath the concentration-time curve is extra delicate than peak focus in assessing the impression of switching on PK similarity.
Our simulation work illustrates {that a} vary of things ought to be fastidiously thought-about when designing a switching examine for the evaluation of interchangeability between two organic merchandise. This text is protected by copyright. All rights reserved.
Biologic therapy for psoriasis in most cancers sufferers: ought to they nonetheless be thought-about forbidden?
Obtainable proof to information clinicians within the administration of psoriasis sufferers with a historical past of malgnancies is scarce. The newest technology of organic medication is historically thought-about to be secure in sufferers with earlier malignancy, though solely case reviews and brief case sequence on using organic medication on this inhabitants can be found within the literature.
On this paper, we current the expertise of our clinic on 37 psoriatic sufferers with a earlier analysis of neoplasia handled subsequently with organic medication. Subsequently, a scientific evaluation of the literature was carried out and 38 instances had been discovered. The primary biologic utilized in our sufferers and the sufferers described within the literature was secukinumab.
In each populations therapy with biologics was secure, illness progressions reported weren’t associated to therapy.Based mostly on our expertise, which is the most important at the moment accessible, and the instances reported within the literature the therapy of psoriasis in sufferers with beforehand recognized most cancers with biologics towards TNFalpha, IL17, IL23 and IL12 would seem like secure. The primary expertise on using Risankizumab and brodalumab on this particular inhabitants can be reported in our sequence.
A Complete Literature Evaluate and Professional Consensus Assertion on Therapeutic Drug Monitoring of Biologics in Inflammatory Bowel Illness
Therapeutic drug monitoring (TDM) of biologics is a quickly evolving subject. We aimed to offer a consensus assertion relating to the scientific utility of TDM for biologics in inflammatory bowel illness (IBD). A modified Delphi technique was utilized to develop consensus statements.
A complete literature evaluation was carried out relating to TDM of biologic therapies in IBD, and 45 statements had been subsequently formulated on the potential software of TDM in IBD. The statements, together with literature, had been then offered to a panel of 10 gastroenterologists with experience in IBD and TDM who anonymously rated them on a scale of 1-10 (1 = strongly disagree and 10 = strongly agree).
An skilled consensus growth assembly was held just about to evaluation, focus on, refine, and reformulate statements that didn’t meet standards for settlement or that had been ambiguous. Throughout the assembly, further statements had been proposed.
Panelists then confidentially revoted, and statements rated ≥7 by 80% or extra of the members had been accepted. Throughout the digital assembly, eight statements had been reworded, 7 new statements had been proposed, and 19 statements had been rerated.
Consensus was lastly reached in 48/49 statements. The panel agreed that reactive TDM ought to be used for all biologics for each major nonresponse and secondary lack of response. It was really helpful that therapy discontinuation shouldn’t be thought-about for infliximab or adalimumab till a drug focus of no less than 10-15 μg/mL was achieved.
Consensus was additionally achieved relating to the utility of proactive TDM for anti-tumor necrosis issue remedy. It was really helpful to carry out proactive TDM after induction and no less than as soon as throughout upkeep. Consensus was achieved normally relating to the utility of TDM of biologics in IBD, particularly for reactive and proactive TDM of anti-tumor necrosis components.
ImmTORTM to amplify the efficacy and cut back immunogenicity of biologics
In latest months as vaccines towards the SARS-CoV-2 virus proceed to rollout throughout the globe, there was a renewed curiosity in methods to activate or ignite the immune system. For a vaccine to be efficient, it should be immunogenic and particular to impress the physique’s defenses to mount an efficient response that protects the host from illness.
Nonetheless, there are different conditions whereby the immune system mounts an undesirable immune response that may be detrimental to well being, both immediately, by inflicting an autoimmune illness, or not directly, by compromising the security and/or efficacy of biologic medication.
In these situations, it might be fascinating to have a ‘tolerogenic vaccine’ that might selectively and successfully mitigate these undesirable immune responses. ImmTORTM, a nanoparticle know-how, is being developed to handle the difficulty of immunogenicity for gene remedy vectors and different biologic medication.
By focusing on antigen-presenting cells, ImmTORTM has the potential to amplify the efficacy of biologic therapies and unlock the total potential of such therapies to enhance the lives of those that endure from critical and debilitating ailments.
Biologic and Esthetic Final result of CAD/CAM Customized Ceramic Implant Abutment: A Scientific Report
A prerequisite of a useful and esthetical implant-supported crown is a correct surgical planning and an abutment with a design and coloration that keep the preliminary soft-tissue contour.
This scientific report describes using a customized ceramic implant abutment designed with computer-aided design and computer-aided manufacturing (CAD/CAM) know-how.
A zirconia framework was milled and cemented further orally to a prefabricated titanium base, the brand new customized abutment being each exact and esthetic.
New insights into the microscopic interactions related to the bodily mechanism of motion of extremely diluted biologics
On this investigation, we report the impact on the microscopic dynamics and interactions of the cytokine interferon gamma (IFN-γ) and antibodies to IFN-γ (anti-IFN-γ) and to the interferon gamma receptor 1 (anti-IFNGR1) ready in exceptionally dilute options of preliminary proteins.
Utilizing each THz spectroscopy and molecular dynamics simulations now we have uncovered that the excessive dilution technique of pattern preparation leads to the reorganization of the pattern floor residue dynamics on the solvent-protein interface that results in each structural and kinetic heterogeneous dynamics that in the end create interactions that improve the binding chance of the antigen binding website.
BCIP (Molecular Biology Grade) |
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| CE109 | GeneOn | 1 g | EUR 90 |
CHAPS (Molecular Biology Grade) |
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| CE114 | GeneOn | 1 g | EUR 55 |
CHAPS (Molecular Biology Grade) |
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| CE115 | GeneOn | 5 g | EUR 131 |
CHAPS (Molecular Biology Grade) |
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| CE116 | GeneOn | 25 g | EUR 410 |
DAPI (Molecular Biology Grade) |
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| CE117 | GeneOn | 5 mg | EUR 60 |
DAPI (Molecular Biology Grade) |
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| CE118 | GeneOn | 25 mg | EUR 133 |
DAPI (Molecular Biology Grade) |
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| CE119 | GeneOn | 100 mg | EUR 319 |
Dimethylsulfoxide (Molecular Biology Grade) |
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| CE120 | GeneOn | 100 ml | EUR 55 |
Dimethylsulfoxide (Molecular Biology Grade) |
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| CE121 | GeneOn | 500 ml | EUR 92 |
DTT (Molecular Biology Grade) |
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| CE131 | GeneOn | 5 g | EUR 78 |
DTT (Molecular Biology Grade) |
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| CE132 | GeneOn | 10 g | EUR 111 |
DTT (Molecular Biology Grade) |
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| CE133 | GeneOn | 25 g | EUR 203 |
Glycine (Molecular Biology Grade) |
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| CE158 | GeneOn | 1 kg | EUR 70 |
Glycine (Molecular Biology Grade) |
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| CE159 | GeneOn | 5 kg | EUR 190 |
HEPES (Molecular Biology Grade) |
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| CE171 | GeneOn | 100 g | EUR 82 |
HEPES (Molecular Biology Grade) |
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| CE172 | GeneOn | 500 g | EUR 224 |
HEPES (Molecular Biology Grade) |
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| CE173 | GeneOn | 1 kg | EUR 354 |
Lysozyme (Molecular Biology Grade) |
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| CE188 | GeneOn | 1 g | EUR 59 |
Lysozyme (Molecular Biology Grade) |
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| CE189 | GeneOn | 10 g | EUR 206 |
NAD (Molecular Biology Grade) |
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| CE196 | GeneOn | 1 g | EUR 60 |
NAD (Molecular Biology Grade) |
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| CE197 | GeneOn | 5 g | EUR 138 |
NBT (Molecular Biology Grade) |
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| CE209 | GeneOn | 1 g | EUR 103 |
NBT (Molecular Biology Grade) |
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| CE210 | GeneOn | 5 g | EUR 300 |
Tris (Molecular Biology Grade) |
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| CE237 | GeneOn | 500 g | EUR 89 |
Tris (Molecular Biology Grade) |
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| CE238 | GeneOn | 1 kg | EUR 128 |
Tris (Molecular Biology Grade) |
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| CE239 | GeneOn | 5 kg | EUR 446 |
Tween20 (Molecular Biology Grade) |
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| CE242 | GeneOn | 1 l | EUR 89 |
Water (Molecular Biology Grade) |
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| CE243 | GeneOn | 500 ml | EUR 52 |
Water (Molecular Biology Grade) |
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| CE244 | GeneOn | 1 l | EUR 56 |
Water, Ultrapure Molecular Biology Grade |
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| 41024-4L | Biotium | 4L | EUR 121 |
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Description: Minimum order quantity: 1 unit of 4L |
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Ammonium sulfate (Molecular Biology Grade) |
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| CE105 | GeneOn | 250 g | EUR 46 |
Ammonium sulfate (Molecular Biology Grade) |
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| CE106 | GeneOn | 1 kg | EUR 60 |
Ammonium sulfate (Molecular Biology Grade) |
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| CE107 | GeneOn | 5 kg | EUR 128 |
Bis-Acrylamid (Molecular Biology Grade) |
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| CE110 | GeneOn | 50 g | EUR 79 |
Bis-Acrylamid (Molecular Biology Grade) |
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| CE111 | GeneOn | 250 g | EUR 216 |
Formamide deionized (Molecular Biology Grade) |
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| CE145 | GeneOn | 500 ml | EUR 73 |
Formamide deionized (Molecular Biology Grade) |
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| CE146 | GeneOn | 1 l | EUR 100 |
Glycerol 87 % (Molecular Biology Grade) |
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| CE154 | GeneOn | 1 l | EUR 78 |
Glycerol waterfree (Molecular Biology Grade) |
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| CE155 | GeneOn | 500 ml | EUR 65 |
Glycerol waterfree (Molecular Biology Grade) |
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| CE156 | GeneOn | 1 l | EUR 85 |
Glycerol waterfree (Molecular Biology Grade) |
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| CE157 | GeneOn | 2.5 l | EUR 142 |
Guanidine - Hydrochloride (Molecular Biology Grade) |
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| CE160 | GeneOn | 100 g | EUR 78 |
Guanidine - Hydrochloride (Molecular Biology Grade) |
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| CE161 | GeneOn | 250 g | EUR 128 |
Guanidine - Hydrochloride (Molecular Biology Grade) |
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| CE162 | GeneOn | 500 g | EUR 194 |
Guanidine - Hydrochloride (Molecular Biology Grade) |
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| CE163 | GeneOn | 1 kg | EUR 294 |
Guanidine Thiocyanate (Molecular Biology Grade) |
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| CE164 | GeneOn | 100 g | EUR 72 |
Guanidine Thiocyanate (Molecular Biology Grade) |
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| CE165 | GeneOn | 500 g | EUR 160 |
Guanidine Thiocyanate (Molecular Biology Grade) |
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| CE166 | GeneOn | 1 kg | EUR 256 |
MOPS buffer (Molecular Biology Grade) |
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| CE194 | GeneOn | 100 g | EUR 85 |
MOPS buffer (Molecular Biology Grade) |
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| CE195 | GeneOn | 250 g | EUR 141 |
Sodium chloride (Molecular Biology Grade) |
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| CE205 | GeneOn | 500 g | EUR 52 |
Sodium chloride (Molecular Biology Grade) |
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| CE206 | GeneOn | 1 kg | EUR 59 |
Sodium chloride (Molecular Biology Grade) |
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| CE207 | GeneOn | 5 kg | EUR 103 |
D(+)-Sucrose (Molecular Biology Grade) |
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| CE224 | GeneOn | 500 g | EUR 56 |
D(+)-Sucrose (Molecular Biology Grade) |
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| CE225 | GeneOn | 1 kg | EUR 70 |
D(+)-Sucrose (Molecular Biology Grade) |
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| CE226 | GeneOn | 5 kg | EUR 173 |
Tris - Hydrochloride (Molecular Biology Grade) |
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| CE234 | GeneOn | 250 g | EUR 83 |
Tris - Hydrochloride (Molecular Biology Grade) |
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| CE235 | GeneOn | 500 g | EUR 120 |
Tris - Hydrochloride (Molecular Biology Grade) |
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| CE236 | GeneOn | 1 kg | EUR 186 |
TritonX-100 (Molecular Biology Grade) |
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| CE240 | GeneOn | 500 ml | EUR 56 |
TritonX-100 (Molecular Biology Grade) |
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| CE241 | GeneOn | 1 l | EUR 66 |
Tween 20, Molecular Biology Grade |
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| T9100-010 | GenDepot | 100ml | EUR 72 |
Tween 20, Molecular Biology Grade |
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| T9100-050 | GenDepot | 500ml | EUR 111 |
Tween 20, Molecular Biology Grade |
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| T9100-100 | GenDepot | 1L | EUR 134 |
Agarose, low EEO, GlenBiol, suitable for molecular biology |
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| GE6258-100G | Glentham Life Sciences | 100 g | EUR 181 |
Water, distilled, GlenBiol™, suitable for molecular biology |
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| GK8512-1L | Glentham Life Sciences | 1 l | EUR 77 |
Crystalline |
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| 5-01010 | CHI Scientific | 10mg | Ask for price |
EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade) |
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| CE135 | GeneOn | 250 g | EUR 60 |
EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade) |
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| CE136 | GeneOn | 500 g | EUR 72 |
EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade) |
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| CE137 | GeneOn | 1 kg | EUR 104 |
EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade) |
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| CE138 | GeneOn | 5 kg | EUR 349 |
D(+)-Glucose waterfree (Molecular Biology Grade) |
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| CE148 | GeneOn | 500 g | EUR 56 |
D(+)-Glucose waterfree (Molecular Biology Grade) |
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| CE149 | GeneOn | 1 kg | EUR 63 |
D(+)-Glucose waterfree (Molecular Biology Grade) |
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| CE150 | GeneOn | 5 kg | EUR 150 |
Yeast extract powder (Molecular Biology Grade) |
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| CE169 | GeneOn | 500 g | EUR 111 |
Hyaluronidase Grade I (Molecular Biology Grade) |
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| CE174 | GeneOn | 1 g | EUR 194 |
Hyaluronidase Grade I (Molecular Biology Grade) |
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| CE175 | GeneOn | 5 g | EUR 767 |
Magnesium acetate - Tetrahydrate (Molecular Biology Grade) |
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| CE190 | GeneOn | 500 g | EUR 82 |
NADH - Disodium salt (Molecular Biology Grade) |
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| CE198 | GeneOn | 1 g | EUR 76 |
NADH - Disodium salt (Molecular Biology Grade) |
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| CE199 | GeneOn | 5 g | EUR 204 |
NADP - sodium salt (Molecular Biology Grade) |
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| CE200 | GeneOn | 250 mg | EUR 77 |
NADP - sodium salt (Molecular Biology Grade) |
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| CE201 | GeneOn | 1 g | EUR 159 |
NADPH - Tetrasodium salt (Molecular Biology Grade) |
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| CE202 | GeneOn | 25 mg | EUR 59 |
NADPH - Tetrasodium salt (Molecular Biology Grade) |
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| CE203 | GeneOn | 100 mg | EUR 105 |
NADPH - Tetrasodium salt (Molecular Biology Grade) |
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| CE204 | GeneOn | 500 mg | EUR 312 |
SSC Buffer (20X) (Molecular Biology Grade) |
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| CE229 | GeneOn | 1 l | EUR 72 |
XTT sodium salt (Molecular Biology Grade) |
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| CE250 | GeneOn | 100 mg | EUR 174 |
XTT sodium salt (Molecular Biology Grade) |
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| CE251 | GeneOn | 500 mg | EUR 510 |
Albumin fraction V (pH7,0) (Molecular Biology Grade) |
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| CE100 | GeneOn | 50 g | EUR 107 |
Albumin fraction V (pH7,0) (Molecular Biology Grade) |
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| CE101 | GeneOn | 100 g | EUR 161 |
Albumin fraction V (pH7,0) (Molecular Biology Grade) |
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| CE102 | GeneOn | 250 g | EUR 323 |
Albumin fraction V (pH7,0) (Molecular Biology Grade) |
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| CE103 | GeneOn | 500 g | EUR 547 |
Albumin fraction V (pH7,0) (Molecular Biology Grade) |
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| CE104 | GeneOn | 1 kg | EUR 969 |
Agarose LE, Ultra-Pure Molecular Biology Grade, 100 g |
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| 41028-100G | Biotium | 100G | EUR 222 |
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Description: Minimum order quantity: 1 unit of 100G |
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Agarose LE, Ultra-Pure Molecular Biology Grade, 25 g |
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| 41028-25G | Biotium | 25G | EUR 109 |
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Description: Minimum order quantity: 1 unit of 25G |
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Agarose LE, Ultra-Pure Molecular Biology Grade, 500 g |
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| 41028-500G | Biotium | 500G | EUR 719 |
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Description: Minimum order quantity: 1 unit of 500G |
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EDTA solution pH 8.0 (0.5 M) (Molecular Biology Grade) |
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| CE141 | GeneOn | 500 ml | EUR 73 |
LB-Agar - Powder according to Lennox (Molecular Biology Grade) |
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| CE178 | GeneOn | 500 g | EUR 91 |
LB-Agar - Powder according to Lennox (Molecular Biology Grade) |
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| CE179 | GeneOn | 2.5 kg | EUR 251 |
LB-Agar - Powder according to Miller (Molecular Biology Grade) |
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| CE180 | GeneOn | 500 g | EUR 87 |
LB-Agar - Powder according to Miller (Molecular Biology Grade) |
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| CE181 | GeneOn | 2.5 kg | EUR 246 |
LB-Medium - Powder according to Lennox (Molecular Biology Grade) |
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| CE182 | GeneOn | 500 g | EUR 90 |
LB-Medium - Powder according to Lennox (Molecular Biology Grade) |
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| CE183 | GeneOn | 2.5 kg | EUR 251 |
LB-Medium - Powder according to Miller (Molecular Biology Grade) |
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| CE184 | GeneOn | 2.5 kg | EUR 246 |
AGAROSE LE, LOW EEO, MOLECULAR BIOLOGY GRADE, 100G PER UNIT |
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| AGR-LE-100 | CORNING | 1/pk | EUR 168 |
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Description: Bioscience Mol Bio; Agarose |
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Phenol |
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| 20-abx184753 | Abbexa |
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100 ML, MOLECULAR BIOLOGY GRADE WATER; TESTED TO USP STERILE PURIFIED WATER SPECIFICATIONS |
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| 46-000-CI | CORNING | 100 mL/pk | EUR 57 |
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Description: Media Catalog; Sterile Wi-Fi Qual, Cell |
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1 L, MOLECULAR BIOLOGY GRADE WATER; TESTED TO USP STERILE PURIFIED WATER SPECIFICATIONS |
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| 46-000-CM | CORNING | 1L/pk | EUR 98 |
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Description: Media Catalog; Sterile Wi-Fi Qual, Cell |
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500 ML, MOLECULAR BIOLOGY GRADE WATER; TESTED TO USP STERILE PURIFIED WATER SPECIFICATIONS |
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| 46-000-CV | CORNING | 500 mL/pk | EUR 106 |
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Description: Media Catalog; Sterile Wi-Fi Qual, Cell |
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AGAROSE LE, LOW EEO, MOLECULAR BIOLOGY GRADE, 500G/UNIT, 10 UNITS PER CASE |
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| AGR-LE-5001 | CORNING | 1/pk | EUR 3058 |
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Description: Bioscience Mol Bio; Agarose |
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AGAROSE MS, PCR SCREENING, MOLECULAR BIOLOGY GRADE, 100G/UNIT, 10 UNITS PER CASE |
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| AGR-MS-1001 | CORNING | 1/pk | EUR 2038 |
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Description: Bioscience Mol Bio; Agarose |
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Crystalline [H-Trp-Gly-OH; MW: 261.2] |
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| SP-55342-1 | Alpha Diagnostics | 1 mg | EUR 141 |
Phenol red |
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| PB0420 | Bio Basic | 25g | EUR 70.88 |
Phenol, 99% |
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| GK6990-100G | Glentham Life Sciences | 100 g | EUR 44 |
Phenol, 99% |
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| GK6990-1KG | Glentham Life Sciences | 1 kg | EUR 78 |
Phenol, 99% |
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| GK6990-500G | Glentham Life Sciences | 500 g | EUR 56 |
Phenol Red |
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| GT9844-100G | Glentham Life Sciences | 100 g | EUR 110 |
Phenol Red |
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| GT9844-250G | Glentham Life Sciences | 250 g | EUR 181 |
Phenol Red |
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| GT9844-25G | Glentham Life Sciences | 25 g | EUR 62 |
Phenol Red |
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| GT9844-5G | Glentham Life Sciences | 5 g | EUR 46 |
Nonyl Phenol |
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| AT037 | Unibiotest | 1mg | EUR 1368 |
Nonyl Phenol |
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| AG037 | Unibiotest | 1 mg | EUR 523 |
Water Phenol |
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| abx082109-250ml | Abbexa | 250 ml | EUR 189 |
AGAROSE LE, LOW EEO, MOLECULAR BIOLOGY GRADE, 100G PER UNIT, 10 UNITS PER CASE |
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| AGR-LE-1001 | CORNING | 1/pk | EUR 772 |
|
Description: Bioscience Mol Bio; Agarose |
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AGAROSE LM, LOW MELTING, MOLECULAR BIOLOGY GRADE, 100G/UNIT, 10 UNITS PER CASE (AL) |
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| AGR-LM-1001 | CORNING | 1/pk | EUR 3737 |
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Description: Bioscience Mol Bio; Agarose |
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AGAROSE LM, LOW MELTING, MOLECULAR BIOLOGY GRADE, 50G/UNIT, 10 UNITS PER CASE (AL) |
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| AGR-LM-501 | CORNING | 1/pk | EUR 2075 |
|
Description: Bioscience Mol Bio; Agarose |
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ELISA kit for Rat PST (Phenol Sulfotransferase) |
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| ELK6740 | ELK Biotech | 1 plate of 96 wells | EUR 432 |
|
Description: A sandwich ELISA kit for detection of Phenol Sulfotransferase from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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ELISA kit for Human PST (Phenol Sulfotransferase) |
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| ELK3246 | ELK Biotech | 1 plate of 96 wells | EUR 432 |
|
Description: A sandwich ELISA kit for detection of Phenol Sulfotransferase from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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ELISA kit for Mouse PST (Phenol Sulfotransferase) |
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| ELK3642 | ELK Biotech | 1 plate of 96 wells | EUR 432 |
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Description: A sandwich ELISA kit for detection of Phenol Sulfotransferase from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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Phenol, saturated (pH7.9) |
|||
| PC6910 | Bio Basic | 100ml | EUR 76.1 |
Phenol, saturated (pH4.5) |
|||
| PC6920 | Bio Basic | 100ml | EUR 76.1 |
4-(Benzyloxy)phenol |
|||
| GP9986-100G | Glentham Life Sciences | 100 g | EUR 118 |
4-(Benzyloxy)phenol |
|||
| GP9986-250G | Glentham Life Sciences | 250 g | EUR 198 |
4-(Benzyloxy)phenol |
|||
| GP9986-25G | Glentham Life Sciences | 25 g | EUR 59 |
Phenol Red Solution |
|||
| CA013-010 | GenDepot | 100ml | EUR 69 |
3-(Aminomethyl)phenol |
|||
| 20-abx185751 | Abbexa |
|
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Phenol, 4-propoxy- |
|||
| 20-abx184303 | Abbexa |
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2-(Aminomethyl)phenol |
|||
| 20-abx185699 | Abbexa |
|
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30UL CLEAR PIPET TIPS FOR MOLECULAR DEVICE LIBERTY. |
|||
| LT-384-R | CORNING | 3840/pk | EUR 2193 |
|
Description: Robotic Tips; Robotic tips - Axygen |
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Recombinant Phenol Sulfotransferase (PST) |
|||
| 4-RPB268Hu01 | Cloud-Clone |
|
|
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Description: Recombinant Human Phenol Sulfotransferase expressed in: E.coli |
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Recombinant Phenol Sulfotransferase (PST) |
|||
| 4-RPB268Mu01 | Cloud-Clone |
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|
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Description: Recombinant Mouse Phenol Sulfotransferase expressed in: E.coli |
|||
Recombinant Phenol Sulfotransferase (PST) |
|||
| 4-RPB268Ra01 | Cloud-Clone |
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|
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Description: Recombinant Rat Phenol Sulfotransferase expressed in: E.coli |
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Phenol red, sodium salt |
|||
| PD0424 | Bio Basic | 25g | EUR 63.92 |
Phenol Red (sodium salt) |
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| HY-D0169A | MedChemExpress | 500mg | EUR 108 |
Phenol Red sodium salt |
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| GT6682-100G | Glentham Life Sciences | 100 g | EUR 142 |
Our outcomes point out that the modified interfacial dynamics of anti-IFN-γ and anti-IFGNR1 that we probe experimentally are immediately related to alterations within the complementarity areas of the distinct antibodies that designate each antigen-antibody affinity and recognition.
